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E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Jul 2024, Vol 11, Issue 3
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Original Article
Effect of Some Herbal Essential Oils on the Content of Compounds With Pharmacological Properties and Oxidative Stability of Black Cumin Seed Oil
Rogaieh Soltani1, Sodeif Azadmard-Damirchi2, Mahdi Gharekhani1, Mohammadali Torbati3
1Department of Food Science and Technology, Tabriz Branch, Islamic Azad University, Tabriz, Iran
2Department of Food Science and Technology, Faculty of Agriculture, University of Tabriz, Tabriz, Iran
3Department of Food Science and Technology, Faculty of Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran

DOI: 10.34172/cjmb.2024.3003
Viewed : 346 times
Downloaded : 492 times.

Keywords : Natural antioxidants, Essential oils, Black cumin seed oil, Oxidative stability, Therapeutic
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Objectives: Thymoquinone is present in Nigella sativa L. seeds which is responsible for the majority of the pharmacological properties. Although synthetic antioxidants are effective in retarding oil oxidation, their use is being limited due to their potential negative health effects.

Materials and Methods: In this study, the effect of essential oils of rosemary, pennyroyal, thyme, mint, peppermint, mastic gum, and frankincense as natural antioxidants in concentrations of 250, 500, 750, and 1000 ppm in comparison with tert-butyl-hydroquinone (TBHQ) (100 ppm) on the quality characteristics of black seed oil and its thymoquinone content during 90 days of storage was studied.

Results: The results showed that the incorporation of essential oils was more effective than TBHQ in increasing oxidative stability and reducing peroxide and acid values. Among essential oils, rosemary was more effective in increasing the oxidation stability index. Rosemary (750 ppm) and mastic gum (500 ppm) were more effective in controlling the peroxide value. The addition of essential oils to black seed oil did not result in a significant alteration (P > 0.05) in the thymoquinone content. However, it did inhibit the decomposition and loss of this compound.

Conclusions: It was concluded that essential oils could be a good alternative to TBHQ for increasing the black seed oil stability, shelf life and preservation. Given the numerous pharmaceutical applications of black seed oil, the findings of this study can be utilized to improve the stability of black seed oil and formulations containing it, as well as to enhance the stability of thymoquinone, which holds therapeutic potential, during storage.


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