Materials and Methods: In this randomized controlled trial, 52 obese and overweight women with body mass index (BMI) ≥25 were evaluated in two intervention and control groups, The intervention was implemented weekly. Triglyceride (TG), high-density lipoprotein (HDL), fasting blood sugar (FBS), blood pressure (BP), BMI, and waistline measurements thyroid tests were assessed measured as the main outcome, and life-quality and sexual function improvement as its secondary outcome in pre, post and follow-up phase.

Results: The study results indicated that the acceptance, mindfulness, and compassion (Kg-free) protocol was effective on the BMI, waistline, TG level, BP (systolic and diastolic index), quality of life, and sexual function in women with overweight and obesity, but fasting BP and HDL level did not significant (d=0.001–0.50; significant at the 0.001 level).

Conclusions: The present trial was carried out aiming to examine the efficacy of group intervention based on acceptance, mindfulness, and compassion on obese and overweighed women and its effect on the components of metabolic syndrome, including the waistline, BMI, BP, FBS, TG, HDL, the quality of life, and the sexual function. Our results showed that group intervention based on acceptance, mindfulness, and compassion could reduce the BMI of the individuals in the intervention group compared to the control group. Moreover, the present study provided further evidence that this intervention bears an essential part in the psychological interventions for individuals struggling with overweight and obesity.