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E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Apr 2023, Vol 10, Issue 2
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Case Report
Gastroduodenal Perforation in a Child With Sickle Cell Anemia: A Case Report
Sanaz Mehrabani1, Hassnan Mahmoodi Nesheli1, Abbas Hadipur1, Leila Moslemi2
1Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
2Health Reproductive Research Center, Sari Branch, Islamic Azad University, Sari, Iran

CJMB 2023; 10: 105-107
DOI: 10.34172/cjmb.2023.16
Viewed : 1441 times
Downloaded : 1484 times.

Keywords : Peptic ulcer, Anemia, Sickle cell, Child
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Objectives: Gastroduodenal perforation (GDP) is a rare cause of acute abdominal pain in children.

Case Presentation: A 12-year-old boy presented with abdominal pain around the periumbilical and epigastric region on 7previous days. His familial history was significant for sickle cell anemia in the mother and minor thalassemia in the father. He had been diagnosed with sickle cell anemia at the age of 4 years and had received blood transfusion and hydroxyurea every month. At physical examination, a distended abdomen and decreased intestinal sounds were seen. Also, he had a history of cholecystectomy (for cholelithiasis). Fecal occult blood was detected, while no Helicobacter pylori antigen was present. Abdominal ultrasound examination revealed splenomegaly and evidence of free fluid. Surgical results showed bile discharge in the abdominal cavity, and perforation of duodenum and pylorus.

Conclusions: Since the symptoms of GDP in children are non-specific, especially in children with sickle cell anemia, it should be considered in these patients with abdominal pain.


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