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E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Jan 2022, Vol 9, Issue 1
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Original Article
The Comparison of the Early Outcomes of Perimembranous Ventricular Septal Defect Closure by Two Different Methods: Transcatheter and Open-Heart Surgery in the Northwest of Iran
Ali Rafiei1, Akbar Molaei1, Ahmad Jamei Khosroshahi1, Mahmood Samadi1, Shamsi Ghaffari1
1Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

CJMB 2022; 9: 038-042
DOI: 10.34172/cjmb.2022.07
Viewed : 1379 times
Downloaded : 1347 times.

Keywords : Ventricular septal defect, Open-heart surgery, Transcatheter, Outcomes
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Objectives: Ventricular septal defect (VSD) is the most common congenital heart disease (CHD) (40%). Traditionally, VSDs have been repaired surgically; however, recently VSD closure by device has been developed. This study aimed to compare these two methods in terms of effectiveness, outcomes, and complications.

Materials and Methods: This study was conducted on VSD patients who were treated by either surgery or trans catheter technique in Madani Heart Center from March 2011 to March 2017. The required data regarding effectiveness, outcomes, and complications were recorded based on the patient"s documents. The extracted data were analyzed by SPSS version 18.0.

Results: A total of 93 patients were enrolled (43 patients in transcatheter [A] and 50 patients in open-heart surgery [B] group) in this study. The gender distribution was approximately the same. The mean age of group A was 10.55 years while it was 8.8 years for group B. The duration of ICU and hospital stay, total hospitalization cost, and frequency of blood products transfusion were significantly lower in group A than in group B. However, postoperative pacemaker insertion, arrhythmias, thromboembolism, and mortality rates did not show any significant difference between the two groups. The success rates in group A and B were 97.7% and 96%, respectively.

Conclusions: The results of our study demonstrated that open-heart surgery, due to its nature, required longer hospital and ICU stay, higher cost, and higher blood transfusion rate than transcatheter therapy, but it was associated with similar complications and success rates. Therefore, device closure in appropriately selected patients is recommended as an alternative to the surgical approach.


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