Login Contact Us
E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Oct 2021, Vol 8, Issue 4
Advanced Search
Title
Authors
Keyword
Poll
How do you find the scientific quality of the published articles on our web site?
Original Article
Evaluation of Serum Selenium Levels in Sepsis Patients Hospitalized in Tabriz
Hamid Owaysee Osquee1, Peyman Eini2, Saleh Bahramnezhad1, Mehdi Haghdoost1
1Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
2School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran

CJMB 2021; 8: 276-282

Viewed : 2630 times
Downloaded : 1779 times.

Keywords : Severe sepsis, Septic shock, Prediction, Etiology, Selenium
Full Text(PDF) | Related Articles
Abstract
Objectives: Selenium (Se) is one of the elements of the body whose deficiency causes immune system weakness. Given that a weak immune system is one of the main causes of sepsis, in this study, it was decided to increase the serum Se level in sepsis patients in hospitals affiliated to Tabriz University of Medical Sciences.

Materials and Methods: In this cross-sectional descriptive study, 82 patients with sepsis (common, severe, and septic shock) were selected using a two-year census sampling ending on March 21, 2019 from Sina and Imam Reza hospitals in Tabriz. Data related to the etiology of the disease, underlying diseases, comorbidities, and inpatient testing were collected for each patient, and serum Se levels were assessed by atomic absorption spectroscopy. To analyze the data, chi-square, t test, and Mann-Whitney U tests were run using SPSS, version 20, and a P value less than 0.05 was considered statistically significant.

Results: The results of a review revealed that the history of underlying diseases [diabetes (P = 0.009), hypertension (P=0.019), and malignancies (P = 0.029)], comorbidities [pneumonia (P = 0.001), malignancy and chemotherapy (P = 0.012), and meningitis (P = 0.009)], and disease etiology [bacteremia of uncertain origin (P = 0.001), pneumonia (P = 0.001), urinary tract infection (P = 0.009), and skin infection (P = 0.005)] was significantly higher in patients with septic shock compared to those with sepsis and severe sepsis. On the other hand, the severity of the disease was significantly associated with a decrease in the serum Se level (P = 0.010).

Conclusions: In general, serum Se levels decrease with the increased severity of sepsis. Thus, measuring Se levels may be helpful in rejecting the progression of the disease.

 

Cite By, Google Scholar

Google Scholar

Articles by Owaysee Osquee H
Articles by Eini P
Articles by Bahramnezhad S
Articles by Haghdoost M

PubMed

Articles by Peyman Eini
Articles by Saleh Bahramnezhad
Articles by Mehdi Haghdoost

Submit Paper
Online Submission System
CJMB ENDNOTE ® Style Tutorials Publication Charge Women's Reproductive Health Research Center About Journal
Publication Information
Publisher
Aras Part Medical International Press Editor-in-Chief
Arash Khaki
Deputy Editor
Zafer Akan
Published Article Statistics