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E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Jan 2022, Vol 9, Issue 1
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Original Article
Evaluation of Intrauterine Adhesion After Hysteroscopic Resection of Uterine Septum
Leili Hafizi1, Maliheh Amirian2, Seyedeh Azam Pourhoseini1, Akram Behrouznia1, Mina Baradaran1
1Department of Obstetrics and Gynecology, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
2Department of IVF and Infertility, Milad infertility Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

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Keywords : Uterine septum, Septoplasty, Metroplasty, Hysteroscopy, Intrauterine adhesion, Synechia
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Objectives: The aim of this study was to evaluate the rate and severity of intrauterine adhesions (IUAs) and their association with septum morphology following the hysteroscopic resection of the uterine septum.

Materials and Methods: This cross-sectional study was conducted on patients with septate uteri undergoing hysteroscopic septolysis with scissors. Two months after the surgery, the second look hysteroscopy was performed and the intrauterine cavity was evaluated for IUAs and residual septum. Afterward, the rate and severity of adhesions and residual septum and their association with the septal morphology were studied as well.

Results: In general, 30 patients were entered into the study. The incidence rate of adhesions following septoplasty was 23.3%. It was mild and moderate in 16.7% and 6.7%, respectively. The incidence rate of adhesions was not related to the length and width of the septum (P = 0.281, P = 0.495). The rate of the residual septum in second-look hysteroscopy was 56.7%, which was less than 0.5 cm in most cases (33.3%). It was not more than 1 cm in any case. The possibility of the residual septum was significantly higher in long septa (P = 0.045) whereas it was not related to the septum width (P = 0.087).

Conclusions: IUA following hysteroscopic septolysis is a possibility, especially in infertile patients which is often mild. The presence of a uterine factor in such patients may justify the risk of increased IUAs in our study in comparison to others. Therefore, it is able to perform second-look hysteroscopy in infertile patients with a septate uterus for the diagnosis and early treatment of IUAs.


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Aras Part Medical International Press Editor-in-Chief
Arash Khaki
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Zafer Akan
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