Login Contact Us
E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Jul 2021, Vol 8, Issue 3
Advanced Search
How do you find the scientific quality of the published articles on our web site?
Original Article
The Relationship Between Attention Deficit Hyperactivity Disorder and Functional Constipation in Patients Referred to Pediatric Gastrointestinal Clinic of the Hospitals of Khorramabad City, Iran
Zeinab Zafari1, Shahram Shokri2, Afshin Hasanvand3, Shokoufeh Ahmadipour1, Khatereh Anbari4
1Department of Pediatrics, Lorestan University of Medical Sciences, Khorramabad, Iran
2Department of Infectious Diseases, Lorestan University of Medical Sciences, Khorramabad, Iran
3Faculty of Medicine, Lorestan University of Medical science, Khoramabad, Iran
4Social Determinants of Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran

CJMB 2021; 8: 179-184

Viewed : 1828 times
Downloaded : 1824 times.

Keywords : ADHD, Functional constipation, Case-control study
Full Text(PDF) | Related Articles
Objectives: Both Functional constipation and attention deficit hyperactivity disorder (ADHD) have a high prevalence among children. The aim of this study was to determine the relationship between functional constipation and ADHD.

Materials and Methods: In this case-control study, 4-12-year-old children who were diagnosed with functional constipation were included in the case group and children with no functional constipation were included in the control group. Diagnosis of functional constipation was performed according to ROME III criteria. All participants were interviewed for ADHD using the Persian version of Conners" Parent Rating Scale (short form). Statistical analysis was performed by Chi-square test for investigating the relationship between functional constipation and ADHD.

Results: A total of 100 children with functional constipation and 147 children without constipation were selected. Among the functional constipation group, 27 (27%) had a high score for ADHD and among the group without functional constipation, 16 (10.0%) had a high score for ADHD. The odds ratio was 3.028 (95% confidence interval = 1.532-5.986; P value = 0.001). There was no statistically significant relationship between constipation and ADHD considering the age and gender.

Conclusions: Functional constipation has a relationship with ADHD. The chance of having ADHD is 3 times higher in children with functional constipation. Further studies, particularly cohort studies, are recommended to assess the incidence of ADHD symptoms in infants with functional constipation in the future. Further studies on the possible pathophysiology of the digestive system and bacterial intestinal flora, especially in early childhood and infancy, are suggested for investigating the development of behavioral disorders and ADHD.


Cite By, Google Scholar

Google Scholar

Articles by Zafari Z
Articles by Shokri S
Articles by Hasanvand A
Articles by Ahmadipour S
Articles by Anbari K


Articles by Zeinab Zafari
Articles by Shahram Shokri
Articles by Afshin Hasanvand
Articles by Khatereh Anbari

Submit Paper
Online Submission System
CJMB ENDNOTE ® Style Tutorials Publication Charge Women's Reproductive Health Research Center About Journal
Publication Information
Aras Part Medical International Press Editor-in-Chief
Arash Khaki
Deputy Editor
Zafer Akan
Published Article Statistics