Chemolithotroph Bacteria: From Biology to Application in Medical Sciences

Elham Kazemi; Saiedeh Razi Soofiyani; Hossein Ahangari; Shirin Eyvazi; Mohammad Saeid Hejazi; Vahideh Tarhriz

E-ISSN : 2148-9696

Crescent Journal of
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Apr 2021, Vol 8, Issue 2

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Original Article
Chemolithotroph Bacteria: From Biology to Application in Medical Sciences
Elham Kazemi¹, Saiedeh Razi Soofiyani^2,3, Hossein Ahangari⁴, Shirin Eyvazi⁵, Mohammad Saeid Hejazi^1,3, Vahideh Tarhriz³
¹Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran ²Sina Educational Research, and Treatment Center, Tabriz University of Medical Sciences, Tabriz, Iran ³Molecular Medicine Research Center, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran ⁴Department of Food Science and Technology, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran ⁵Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
CJMB 2021; 8: 081-089 Viewed : 2133 times Downloaded : 4510 times. Keywords : Chemolithotroph bacteria, Secondary metabolites, Enzymes, Medical sciences
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Abstract

Chemolithotrophs are specific bacteria that utilize inorganic compounds as their energy source. These bacteria as the main source of organic molecules have more advantages in various sciences. Unlike phototrophic and organotrophic bacteria which generate their energy via the fascination of sunlight or oxidation of complex organic molecules, chemolithotrophic bacteria can exploit unconventional sources of energy, including various industrial wastes . Therefore, chemolithotroph bacteria play a key role in the remediation of micropollutants such as synthetic hormones, pharmaceutical residues, and sanitary wastes. In addition, secondary metabolites including organic acids, enzymes, and antibiotics derived from these bacteria can be used as pharmaceutical compounds. It seems that the discovery and study of the novel chemolithotrophic bacteria and investigation of their features can be helpful in medical and pharmaceutical sciences. Accordingly, it was attempted to present a comprehensive review on chemolithotrophic microbes, their energy sources, and their applications.