Login Contact Us
E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Oct 2019, Vol 6, Issue 4
Advanced Search
How do you find the scientific quality of the published articles on our web site?
Original Article
Comparative Outcome of Different Types of Redo Surgery in Malfunction of Mechanical Prosthetic Mitral Valve
Babak Nasiri1, Naser Khezerlou Aghdam1, Rezayat Parvizi1, Mohamadreza Taban Sadeghi1, Sanaz Mousavi2, Nasrin Khaki1
1Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
2Gynecology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

CJMB 2019; 6: 529–534

Viewed : 1957 times
Downloaded : 1626 times.

Keywords : Cardiac valve prosthesis, Heart valve prosthesis implantation, Bioprostheses
Full Text(PDF) | Related Articles

Objectives: Redo mitral valve replacement (MVR) is an important therapeutic approach in patients with the malfunction of the prosthetic mitral valve, especially in patients with severe dyspnea or a large thrombus burden. Redo replacement (MVR) and thrombectomy are different surgical approaches in these patients. This study evaluated the outcome of the second
mitral valve surgery including mechanical MVR (M-MVR), biologic MVR (B-MVR), and surgical thrombectomy.

Materials and Methods: To this end, 71 patients were included in this study, who underwent second mitral valve surgery following the malfunction of the prosthetic mitral valve in the last 10 years. These patients were divided into M-MVR, B-MVR, and surgical thrombectomy groups and their demographic, clinical, echocardiographic, and laboratory findings were gathered as well. Then, the patients were evaluated for their third MV surgery if it was performed, followed by evaluating the pump time and cross-clamp time.

Results: Fifty-seven, 8, and 6 patients underwent M-MVR, B-MVR, and thrombectomy, respectively. Based on the results, the mortality rate was not signifcantly different between the 3 groups (P=0.059). In addition, 12 patients underwent the third surgery with the highest (100%) and lowest (0%) rates at thrombectomy and B-MVR groups, respectively. Higher pump time and cross-clamp time were signifcantly associated with an increased mortality rate (P=0.014 and P=0.026, respectively).

Conclusions: In the malfunction of the prosthetic mitral valve, mortality rate failed to signifcantly differ between the patients undergoing M-MVR, B-MVR, and thrombectomy but third surgery is often needed after thrombectomy. It seems that the replacement of previous prosthetic valve with a new mechanical or biological valve yields better results in the case of prosthetic valve malfunction.


Cite By, Google Scholar

Google Scholar

Articles by Nasiri B
Articles by Khezerlou Aghdam N
Articles by Parvizi R
Articles by Taban Sadeghi M
Articles by Mousavi S
Articles by Khaki N


Articles by Babak Nasiri
Articles by Rezayat Parvizi
Articles by Sanaz Mousavi
Articles by Nasrin Khaki

Submit Paper
Online Submission System
CJMB ENDNOTE ® Style Tutorials Publication Charge Women's Reproductive Health Research Center About Journal
Publication Information
Aras Part Medical International Press Editor-in-Chief
Arash Khaki
Deputy Editor
Zafer Akan
Published Article Statistics