|Effects of Dust Micro Particles of Asalouyeh Area on the Thyroid and Parathyroid Glands in Rat|
|Fereshteh Maleki1, Negar Chahibakhsh2, Azadeh Aminian3, Mostafa Mohammadi4, Habibollah Nazem1, Alireza Chamkori5, Afshar Bargahi6, Parviz Farzadinia7|
|1Department of Biochemistry, Payame Noor University of Taft, Yazd, Iran
2Department of Nutrition, Health Chancellery, Bushehr University of Medical Sciences, Bushehr, Iran
3Master Student of Psychiatric Nursing, Yasuj University of Medical Sciences, Yasuj, Iran
4Young Researchers and Elite Club, Bushehr Branch, Islamic Azad University, Bushehr, Iran
5Department of Biology Development, Faculty of Basic Sciences, Islamic Azad University, Kazerun Branch, Kazerun, Iran
6The Persian Gulf Marine Biotechnology Research Center, Bushehr University of Medical Sciences, Bushehr, Iran
7Department of Biology and Anatomical Sciences, Faculty of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran
CJMB 2019; 6: 279-284
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Keywords : Dust, Air pollution, Asalouyeh, Thyroid, Parathyroid
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Objectives: The aim of this study was to evaluate possible changes in thyroid and parathyroid glands tissues and functional structures.
Materials and Methods: About 30 adult male rats were divided into 3 groups: control, negative control (exposed to dust in the clean area free from oil contaminants), and the treatment group (exposed to dust in the polluted area of Asalouyeh with oil hydrocarbons). Before grouping, all the animals were co-cycled. After 25 days of treatment, changes in pancreatic tissue and serum levels of thyroid and parathyroid hormones were measured. Moreover, the amount of heavy metals including lead, cadmium, arsenic, and mercury in animals" serum were measured using atomic absorption.
Results: The amount of heavy metals like lead, cadmium, arsenic, and mercury showed a significant increase in the serum of animals in treatment group compared to negative control and also control groups (P ≤ 0.05). Serum levels of thyroid and parathyroid hormones in treatment group showed a significantly decrease in comparison with control groups. In addition, histological investigations demonstrated relative changes in tissue and functional structures of important thyroid and parathyroid glands tissues.
Conclusions: Dust of Asalouyeh polluted air had relative toxicity effects on thyroid and parathyroid tissues and their hormones.
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