Materials and Methods: This study was conducted during September 2016- February 2017 on 50 patients with endometrioid adenocarcinoma, detected by the diagnostic curettage which was the total abdominal hysterectomy and bilateral salpingo-oophorectomy (TAH + BSO) surgery candidate in the oncology ward of Al-Zahra hospital of Tabriz. Tissue samples of TAH + BSO patients sent for FS pathology were evaluated in terms of histological subtype criteria including endometrioid, serous, clear cell, undifferentiated, tumor grade 1, 2, and 3, tumor size in cm smaller or bigger than 2 cm, and myometrial invasion (MI) rate higher or lower than 50 %. FS results were compared to the final results of the paraffin section (PS) pathology.

Results: The concordance rate between PS and FS regarding the risk factors of endometrioid (k: 0 .492, P < 0.001), myometrium invasion (k: 0.729, P < 0.001), tumor size (k: 0.800, P < 0.001), tumor grade (k: 0.641, P < 0.001), undifferentiated (k: 0.545, P < 0.001), adenosquamous (k: 0.390, P < 0.005), papillary serous (k: 0.658, P < 0.001), and clear cell (k: 0.479, P < 0.001) was 49, 73, 80, 64, 54, 39, and 65 %, respectively.

Conclusions: Based on the results, if FS is accurately and precisely implemented, an appropriate decision can be taken for low-risk patients. This method can successfully be adopted by the gynecologic oncologists.