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E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Oct 2017, Vol 4, Issue 4
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Original Article
High Sensitive CRP in Behcet Disease With and Without Uveitis Compared With Idiopathic Uveitis: A Cross-Sectional Study
Maryam Sahebari1, Zeid Zerehsaz1, Aida Javanbakht1, Zahra Mirfeizi1
1Rheumatic Diseases Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

CJMB 2017; 4: 173–176

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Keywords : Behcet syndrome, High sensitive C-reactive protein, hs-CRP, Uveitis, Idiopathic uveitis
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Background: Uveitis is one of the important manifestations of Behcet disease (BD). High sensitive C-reactive protein (hs-CRP) is an acute phase reactant, which may increase in BD. There are controversies in different studies regarding the relation between hs-CRP and uveitis in BD. This study aimed to determine serum values of hs-CRP and its relationship with uveitis in BD.

Methods: A total of 94 patients, divided into 3 groups (Behcet"s uveitis (n = 31), Behcet"s without uveitis (n = 37) and idiopathic uveitis (n = 26), participated in the study. Serum levels of hs-CRP were compared among those groups.

Result: The mean serum hs-CRP level was 6.49 ± 3.27 mg/L (BD with uveitis), 6.41 ± 3.85 mg/L (BD without uveitis) and 6.97±3.9 mg/L (idiopathic uveitis. Tukey test was done among groups and there were no significant differences between them (P = 0.69).

Conclusion: Our results revealed no significant difference among the 3 groups regarding the mean serum hs-CRP level. However, further studies are warranted in this regard.


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