Materials and Methods: This research was a descriptive study. The study population included patients admitted to the cardiac care unit of Shahid Madani Hospital, Tabriz, Iran, with a diagnosis of AMI from September 2012 until March 2014. Data were collected by using a checklist and the findings of the study were analyzed by SPSS software.

Results: Of the 116 hospitalized patients, 78 (67.5%) were male and 37 (32.5%) were female, and the largest percentage of infected patients was in the age group of 60-70 years [n = 38 (33%)]. Regarding cardiac risk factors, 57 (49%) of patients were hyperlipidemic, 36 (31%) were diabetic, 34 (30%) had high blood pressure, 25 (21%) were smokers, and 21 (18%) had a positive family history of cardiac problems. Patients who were admitted with a diagnosis of AMI, in 53 (46%) cases had streptokinase injection, and in 86 (74%) complications had occurred during drug injection; 87 (75%) patients had dysrhythmia and 29 (25%) had bleeding. Common dysrhythmia was premature ventricular contraction (PVC) with 90 (78.2%) cases. Moreover, 53 (46%) patients had slow ventricular tachycardia (VT), 18 (16%) had premature atrial contraction (PAC), and 5 (4%) had other arrhythmias. Mean of creatine phosphokinase (CPK) was 604, lactic dehydrogenase (LDH) 565.4, creatine phosphokinase mb (CKmb) 58.2, and cardiac troponin I (CTNI) 8.7.

Conclusion: By the timely referral of patients and knowledge of the nurses about complications of streptokinase, its side effects can be prevented.