Original Article | |
Effect of Allium cepa Seed Extract on Serum Testosterone in Rats | |
Vahid Vahdani1, Arash Khaki2 | |
1Department of Pathobiology, Tabriz Branch, Islamic Azad University, Tabriz, Iran 2Women's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran |
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CJMB 2014; 1: 110-112 Viewed : 3088 times Downloaded : 3357 times. Keywords : Allium cepa Seed, Extract, Testosterone |
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Abstract | |
Objective: Allium cepa has been used throughout history as a medicinal drug. It has many compounds
mostly containing sulfur, such as dialkyl disulfide (Alicin), diallyl disulfide (DAS), that are the cause of its
antioxidant and protective properties. The aim of this study was to investigate the effects of this extract on
serum testosterone in rats. Materials and Methods: In the present study, 30 male rats were randomly divided into 3 groups; control group (n = 10), extract group 1 (n = 10), and extract group 2 (n = 10). Extract group 1 and 2, respectively, received 0.5 cc and 1 cc Allium cepa seed extract for 60 consecutive days using gavage method. On the 60th day of study, 5 cc blood samples were obtained from the tail vein of each rat for analyses of serum testosterone. Results: The results show that serum testosterone level increased in the extract groups. Conclusion: Allium cepa seed extract has beneficial effects on serum testosterone; however, further research is necessary in order to gain more knowledge on the mechanism of action of this extract. |
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