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E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Nov 2014, Vol 1, Issue 3
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Review
A Study of Brucella Infection in Humans
Mohammad Reza Hasanjani Roushan1, Sohrab Kazemi2, Fatemeh Fallah Rostami3, Soheil Ebrahimpour1
1Infectious Diseases and Tropical Medicine Research Center, Babol University of Medical Sciences, Babol, Iran
2Cellular and Molecular Research Center, Babol University of Medical Sciences, Babol, Iran
3Undersecretary For Research and Technology, Ministry of Health and Medical Education, Pediatric Neuro Rehabilitation Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran

CJMB 2014; 1: 069-075

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Keywords : Diagnostic test, Human Brucellosis, Therapeutic Regimen, Zoonotic
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Abstract
Objective: Brucellosis is the most usual zoonotic disease around the world especially in the Middle East, Mediterranean and Indian sub-continent areas. This bacterium has ten species that Brucella melitensis among them recognized as the most important cause of human brucellosis. This infection transfer ways to human include of wounds, bacteria inhalation and consumption of septic dairy such as raw milk, cream and butter. Brucellosis as a systemic disease can involve more organs of patients that have symptoms such as fever, night sweating, and backache. This infection can be divided as acute, sub-acute and chronic forms according to the manner of clinical presentation.

Materials and Methods: This research is a review study and conducted by reviewing of the literature, which is related to this issue and also visiting, PubMed, and other linked websites.

Results: In human brucellosis domestic animals are the main natural reservoir of infection. Whenever incidence rate of this infection in domestic and wild animals is reduced on the other hand incidence rate in human also will reduce.

Conclusion: Blood cultures, serological tests and molecular tests are common laboratory methods of this infection. Diminution of relapse and therapeutic failure rates are as most important aim, which is researcher’s regards.

 

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