Lipid Profile in Women with Polycystic Ovary Syndrome

Leila Amini; Mohammad Reza Sadeghi; Fatemeh Oskuie; Koorosh Kamali; Haleh Maleki

E-ISSN : 2148-9696

Crescent Journal of
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Original Article
Lipid Profile in Women with Polycystic Ovary Syndrome
Leila Amini¹, Mohammad Reza Sadeghi², Fatemeh Oskuie³, Koorosh Kamali⁴, Haleh Maleki⁴
¹Department of Midwifery, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran ²Monoclonal Antibody Research Center, Avicenna Research Institute, Academic Center for Education Culture and Research (ACECR), Tehran, Iran ³Nursing Care Research Center AND School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran sup>4Reproductive Biotechnology Research Center, Avicenna Research Institute, Academic Center for Education Culture and Research (ACECR), Tehran, Iran
CJMB 2014; 1: 147-150 Viewed : 2971 times Downloaded : 2391 times. Keywords : Apolipoprotein A-1, Apolipoprotein B Dyslipidemias, Lipids, Polycystic Ovary Syndrome
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Abstract

Objective: Polycystic ovary syndrome (PCOS) is a disorder of hyperandrogenemia and chronic anovulation, which affects 5-10% of all women. It has been reported that women with PCOS often have serum lipid level elevation. This study compares serum lipid levels in women with and without PCOS. Materials and Methods: Lipid profile [total cholesterol (TC), apolipoprotein A-I, apolipoprotein B, high-density lipoprotein (HDL), low density lipoprotein (LDL), triglyceride (TG), and lipoprotein a] in this comparative cross-sectional study were compared between 33 women with and 44 women without PCOS. All biochemical tests were done using fasting blood samples which were frozen in −80 °C since the previous study. Other data were collected from Iranian twin bank. Data were analyzed with SPSS. P < 0.05 considered as significant level. Results: There was no significant difference between two groups in terms of age, age of menarche and body mass index (BMI). Serum levels of TC, apolipoprotein B, apolipoprotein A-1, HDL, LDL, TG, and lipoprotein did not show any difference between two groups. TG in PCOS women with BMI >25 was significantly higher in comparison with non-PCOS. Conclusion: The present study does not support the notion that PCOS affects serum lipid levels except in the term of TG in PCOS women with BMI > 25. It is suggested to repeat this study within PCOS patients who are insulin resistance.