Materials and Methods: This applied research was conducted by a descriptive method (qualitative content analysis document study and fuzzy Delphi method) from 2019 to 2020. The thirty two valid document studies were used to examine the sources and extract the required components of the therapeutic information variable. The content analysis method was used to classify effective components. Participants in this study were 10 experts. Qualitative content analysis of the data obtained through software 2018 MAXQDA.

Results: Two hundred and seventeen primary codes were extracted, reduced to 112 codes after continuous review, and finally these codes were divided in two main themes (categories), including: A- Information; health literacy (1- Information acquisition, 2- Information identification, 3- Information sharing, 4- Awareness-raising, 5- Information needs, and 6- Health knowledge), B- Treatment; health services (7- Patient satisfaction, 8- Information-seeking behavior, 9- Treatment method and cost, 10- Participatory care and information use, 11- Health education, and 12- Disease prevention).

Conclusions: The results showed information therapy approach in medical centers of the country, as a dynamic platform to support clinical decisions of specific diseases (such as immunodeficiency diseases), requires long-term policy to improve research and educational activities. The services of the medical staff will be possible through the establishment of factors and effective elements in retrieving and accessing up-to-date information by the physician and the patient, and as a result, promoting health knowledge in this field.