|Studying the Relationship Between Hypothyroidism and Breast Cancer|
|Sevda Jenabzadeh1, Babak Abri Aghdam1|
|1Department of Surgery, Tabriz Branch, Islamic Azad University, Tabriz, Iran|
CJMB 2019; 6: 096-099
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Keywords : Hypothyroidism, Breast cancer, T3, T4, TSH
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Objectives: Breast cancer is one of the most common diseases in women and hypothyroidism is an important risk factor for developing this cancer. Therefore, the present study aimed to investigate the relationship between hypothyroidism and breast cancer development in women. In addition, the effect of age and weight on hypothyroidism was studied in patients with breast cancer.
Materials and Methods: A total of 200 women who referred to Shams, Amir-al-Momenin, and Noor-Nejat hospitals of Tabriz located in East Azarbijan were selected during a 4-month period in order to participate in this case study. The participants included 100 women with a definite diagnosis of breast cancer vs. 100 healthy women. The levels of thyroid hormones (T3, T4, & TSH) were analyzed and the correlation between these levels and the incidence of breast cancer was determined.
Results: Based on the findings, no significant difference was observed between both groups regarding the age, weight, and levels of thyroid hormones (P > 0.05). Further, the results revealed that the correlation between the age and weight of the studied women and the level of hormones was negligible. However, in patients with breast cancer, there was a significant relationship between T3 serum level and age (P = 0.005).
Conclusions: Generally, no significant relationship was found between the development of breast cancer and hypothyroidism in the patients with breast cancer.
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