|Dose Drinking Water Hardness Have Relationships with Coronary Artery Disease Severity Based on Angiographic Finding in East Azerbaijan Province-Iran?|
|Babak Nasiri1, Naser Khezerloy Aghdam1, Ahmad Separham1, Ramin Salmasi1, Nilgoon Daviran1, Raziyeh Parizad2, Mohammadreza Taban Sadeghi 1|
|1 Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
2 Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran
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Keywords : Calcium, Magnesium, Drinking water hardness, Atherosclerosis
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Objectives: Cardiovascular diseases (CVD)are a major cause of hospital admissions and the main reason of mortality in the world that are triggered by both genetic and environmental factors. Minerals and trace elements have long been considered potential risk factors for CVDof which calcium and magnesium might play a significant role.
The purpose of this study is to assess the relationship between coronary atherosclerotic diseases and hardness of drinking water in the residence of patients admitted to Tabriz"s ShahidMadani Hospital.
Materials and Methods: The research process began following approval of the proposal in the Research Committee of Tabriz University of Medical Sciences and permission by the Ethics Committee. A total of 780 patients had undergone coronary angiography during the process of whom 233 were excluded because of either not meeting inclusion or meeting exclusion criteria. The subjects were then divided into 5 groups based on the severity of coronary artery involvement: group 0 with the least or no involvement; group 1 with one artery involved; group 2 with two arteries involved; group 3 with three arteries involved; and group 4 with severe diffuse involvement of all coronary arteries. Residences of the patients were located from their medical history and 200-ml samples of drinking water were then taken from each area in plastic containers and the levels of calcium and magnesium were measured using EDTA method. Samples were divided into four groups according to the hardness of water.
Results: The mean age of the participants were 59.7 years. The most frequent type of water in the residence areas was soft water. The highest frequency in terms of the severity of atherosclerosis was in group 4 and 3. No significant relationship was found between the severity of atherosclerosis and calcium level of water and between the severity of atherosclerosis and magnesium level of water.
Conclusion: Results show that no significant relationship between could be found between the levels of calcium and magnesium in the drinking water of the patients residing in East Azerbaijan Province and their severity of atherosclerosis.Our findings suggest that the drinking water of the Province can be divided into hard and soft water and the severity of atherosclerosis of the patients is independent of the hardness of drinking water in their residences.
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