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E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Jan 2019, Vol 6, Issue 1
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Original Article
Comparison of Early and late Postpartum Glucose Tolerance Test in Patients with Gestational Diabetes Mellitus
Sedigheh Hantoushzadeh1, Sanaz Mousavi2, Naser Khezerlouy Aghdam3, Farnaz Sahaf2
1Department of obstetrics and gynecology, vali-Asr hospital, Tehran University of medical sciences, Tehran, Iran
2Department Obstetrics & Gynecology, women’s reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
3Department of cardiology, Shahid Madani Hospital, Tabriz University of Medical Sciences, Tabriz, Iran

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Keywords : Gestational diabetes, Postpartum screening, Glucose tolerance test
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Objectives : To evaluate if postpartum diabetes mellitus screening could be done during post delivery hospitalization.

Materials and methods: This case series study was performedin women with gestational diabetes who had normal plasma sugar after delivery.130 women with GDM take 75 gr oral glucose tolerance test (OGTT) before hospital discharge and repeated the test 6 to 12 weeks later.

Results: In this study 130 women were participated, 107(82.3%) patients were analyzed. Early OGTT, was abnormal in 46 cases (43.0%); prediabetes in 34 (31.8%), diabetes in 12 (11.2%). 6 to 12 weeks later OGTT was abnormal in 28 cases (25.2%); 22 (20.6%) prediabetes and 6(5.6%) diabetes. In 5 patients (4.7%) with normal early OGTT, 6 to 12 weeks later OGTT was abnormal (prediabetes and diabetes).  There was a significant association between results of early OGTT and 6 to 12 weeks later OGTT (p = 0.00). Early OGTT was able to detect prediabetes and diabetes (abnormal results) with a sensitivity of 82.14% (95% CI, 63.11-93.94), specificity of 70.89% (95% CI, 59.58-80.57).

Conclusion:Early postpartum screening effectively diagnoses women who are at high risk of diabetes mellitus and need to undergo OGTT 6 weeks later. Identifying high risk patients who need to return 6 to 12 weeks later, eases the management of patients and sensitize patients to come back to check.


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