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E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Jan 2019, Vol 6, Issue 1
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Original Article
Comparing Early and Late Postpartum Glucose Tolerance Test in Patients With Gestational Diabetes Mellitus
Naser Khezerlouy Aghdam1, Sanaz Mousavi2, Sedigheh Hantoushzadeh3, Farnaz Sahaf4
1Department of Cardiology, Tabriz University of Medical Sciences, Shahid Madani Hospital, Daneshgah Street, Tabriz, Iran
2Women’s Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
3Department of Obstetrics and Gynecology, Bagher-Khan Street, Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
4Women’s Reproductive Health Research Center, Alzahra Hospital, Artesh Street, Tabriz University of Medical Sciences, Tabriz, Iran

CJMB 2019; 6: 123-128

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Keywords : Gestational diabetes, Postpartum screening, Glucose tolerance test
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Abstract
Objectives: The present study aimed to evaluate if postpartum diabetes mellitus screening can be performed during post-delivery hospitalization.

Materials and Methods: This case series study was conducted on 130 women with gestational diabetes mellitus (GDM) who had normal blood sugar after the delivery. They took 75 g oral glucose tolerance test (OGTT) before hospital discharge and repeated the test 6-12 weeks later.

Results: Totally, 107 (82.3%) patients out of the total participated women were analyzed. Early OGTT, prediabetes, and diabetes were abnormal in 46 (43.0%), 34 (31.8%), and 12 (11.2%) cases, respectively. In addition, they above-mentioned variables were found to be abnormal in 28 (25.2%) 22 (20.6%), and 6 (5.6%) cases 6-12 weeks later. Further, 6-12 weeks later, the OGTT was abnormal (prediabetes and diabetes) in 5 patients (4.7%) with normal early OGTT. Therefore, there was a significant association between the results of early OGTT and those of 6-12 weeks later (P = 0.00). It implies that early OGTT could detect prediabetes and diabetes (abnormal results) with a sensitivity of 82.14% (95% CI, 63.11-93.94) and specificity of 70.89% (95% CI, 59.58-80.57).

Conclusions: In general, early postpartum screening effectively diagnosed women who were at high risk of diabetes mellitus and needed undergoing OGTT 6 weeks later. Identifying high-risk patients who need to return later facilitates the management of patients and sensitizes patients to refer for further examination.

 

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