|Prevalence of Hypofibrinogenemia In Patients With Acute Gastrointestinal Bleeding: A cross Sectional Study|
|Afshin Amini1, Hamidreza Hatam Abadi 1, Hamid Kariman1, Farinaz Fattahi1, Mohamad Reza Rezaei1|
|1Department of Emergency Medicine, Imam Hossein Hospital , Shahid Beheshti University of Medical Sciences, Tehran, Iran|
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Keywords : Hypofibrinogenemia, Gastro intestinal bleeding, Fibrinogen, Blood
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Objectives: Hypofibrinogenemia can worsen the outcome in patients with gastrointestinal bleeding (GIB). There are a few national surveys on the issue. We conduct this study to evaluate the prevalence of hypofibrinogenemia and its effect on outcome in patients with acute gastrointestinal bleeding.
Materials and Methods: In this cross-sectional study, all data about patients with acute gastrointestinal bleeding admitted in emergency departments of Shahid Beheshti Medical University hospitals in 2016 were calculated and analyzed using SPSS 21 statistical software and all tests were considered significant on 0.05 level.
Results: Sixty nine (69%) percent of patients were male and the mean age was 53.38±13.18 years old. Mean level of haemoglobin, INR and fibrinogen were 10.68, 1.65 and 250.43 respectively. Most cases of hypofibrinogenemia had liver disorders or lower GIB (p<0.05). fibrinogen level had no significant effect on mortality.
Conclusions: Afibrinogenemia is mostly correlated with liver diseases and lower GI bleeding and can cause severe morbidity.
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