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E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Jan 2019, Vol 6, Issue 1
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Short Communication
Prevalence of Hypofibrinogenemia In Patients With Acute Gastrointestinal Bleeding: A cross Sectional Study
Afshin Amini1, Hamidreza Hatam Abadi 1, Hamid Kariman1, Farinaz Fattahi1, Mohamad Reza Rezaei1
1Department of Emergency Medicine, Imam Hossein Hospital , Shahid Beheshti University of Medical Sciences, Tehran, Iran


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Keywords : Hypofibrinogenemia, Gastro intestinal bleeding, Fibrinogen, Blood
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Abstract

Objectives: Hypofibrinogenemia can worsen the outcome in patients with gastrointestinal bleeding (GIB). There are a few national surveys on the issue. We conduct this study to evaluate the prevalence of hypofibrinogenemia and its effect on outcome in patients with acute gastrointestinal bleeding.

Materials and Methods: In this cross-sectional study, all data about patients with acute gastrointestinal bleeding admitted in emergency departments of Shahid Beheshti Medical University hospitals in 2016 were calculated and analyzed using SPSS 21 statistical software and all tests were considered significant on 0.05 level.

Results: Sixty nine (69%) percent of patients were male and the mean age was 53.38±13.18 years old. Mean level of haemoglobin, INR and fibrinogen were 10.68, 1.65 and 250.43 respectively. Most cases of hypofibrinogenemia had liver disorders or lower GIB (p<0.05). fibrinogen level had no significant effect on mortality.

Conclusions: Afibrinogenemia is mostly correlated with liver diseases and lower GI bleeding and can cause severe morbidity.

 

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Aras Part Medical International Press Editors in Chief
Arash Khaki
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Zafer Akan Deputy Editor
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