|The Association Between The Serum Level of 25-hydroxy Vitamin D And the Echocardiographic Indices of Left Ventricular Function In Patients with Non Significant Coronary Artery Disease|
|Kamal Khadem Vatan1, Venus Shahabi Raberi1, Naser Khalili1, Sahar Ajdari 1|
|1Department of Cardiology and Cardiovascular Medicine ,Urmia University of Medical Sciences, Urmia, Iran|
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Keywords : 25-hydroxy vitamin, LV diastolic function, LV systolic function Slow coronary flow; coronary artery disease
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Objectives: Multiple studies has shown that vitamin D deficiency can increase risk of cardiovascular disorders. Role of vitamin D in increasing risk of coronary atherosclerotic disorders and cardiac dysfunction is not yet clear. The present study aimed to assess the relationship between the serum level of vitamin D and the echocardiographic indices of left ventricular function or valvular defects.
Materials and Methods: This cross-sectional study was performed on 80 consecutive patients who were candidate for diagnostic coronary angiography and without evidences of CAD, but with evidences of SCF or minimal CAD. The serum level of 25-hydroxy vitamin D was measured by ELISA method .in order to evaluate the systolic and diastolic function of the left ventricle, patients were evaluated with transthoracic 2D ,Doppler echocardiography and TDI.
Results: Based on angiography reports, 36.2% had normal coronaries, while 50.0% was diagnosed to have isolated minimal CAD, 7.6% had isolated SCF and 6.2% had a combination of minimal CAD and SCF .The mean serum level of 25-hydroxy vitamin D in our patients was 30.33 ± 19.27. The mean level of 25-hydroxy vitamin D was 29.37 ± 22.16 in normal coronary group, 30.39 ± 16.22 in patients with isolated minimal CAD, 18.24 ± 4.32 in patients with concurrent minimal CAD and SCF and 44.65 ± 25.52 in those with isolated SCF ;indicating nonsignificant difference in 25-hydroxy vitamin D concentration across the groups (p = 0.147). The level of 25-hydroxy vitamin D was not associated with the echocardiography indices of left ventricular function or valvular defects, as well.
Conclusion: The serum level of 25-hydroxy vitamin D may not be a predictive factor for of left ventricular function or valvular defects.
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