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E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Oct 2018, Vol 5, Issue 4
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Original Article
Clinical Patterns and Causes of Posterior Uveitis in a Tertiary Referral Eye Center in the Northwest of Iran
Leila Alizadeh Ghavidel1, Mehdi Arshadi2, Farideh Mousavi1
1Department of Ophthalmology, Nikookakari Eye Center, Tabriz University of Medical Sciences, Tabriz, Iran
2Department of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran

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Keywords : Posterior uveitis, Etiology, Iran
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Objectives: Posterior uveitis is the second most common anatomical type of uveitis after the anterior in Iran. The incidence and etiologies are not identical in populations with different races and socioeconomics. In this research, we intend to evaluate the causes of posterior uveitis in a referral center in the Northwest of Iran.

Materials and Methods: In this cross-sectional retrospective study, clinical records of 120 patients with posterior uveitis referred to the Uveitis Clinic at the Nikookari Hospital from 2003 to 2017 have been reviewed. Demographic findings, etiologies, clinical courses, associated systemic diseases, and ocular complications were analyzed.

Results: Infectious etiologies were found in 69.2% of patients withposterior uveitis. The most common etiology of posterior uveitis was toxoplasmosis (59.2%) , andsubsequently, idiopathic (10.8%) and Behçet’s disease (8.3%). Macular scar (5.83%) and macular edema (15%) were the most common complications in patients. Posterior uveitis was seen in 20.8% patients in association with a systemic disease.Behçet’s disease (8.3%) and Vogt-Koyanagi-Harad (VKH) (4.2%) were the most prevalent concomitant diseases.  Non-granulomatous uveitis was observed in 84.2% of cases.The course of the disease was acute in 83.33% of patients.

Conclusion: This study revealed that infectious etiologies were the most common causes of posterior uveitis. Toxoplasmosis and Behcet's disease were the most frequent cases. The most common complication of posterior uveitis was macular scar. It seems that identifying and analyzing causes of the posterior uveitis and its complications are crucial for the development of policies and treatment guidelines.


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Aras Part Medical International Press Editors in Chief
Arash Khaki
Zafer Akan Deputy Editor
Javadi, Leila
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