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E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Jan 2019, Vol 6, Issue 1
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Original Article
The Frequency of Psychiatric Disorders in Cystic Fibrosis Patients Aged 5-18 Years in Northwest of Iran
Seyedeh Shaghayegh Hosseinzadeh1, Mandana Rafeey2, Leila Vahedi2, Seyed Gholamreza Noorazar1
1Research Center of Psychiatry and Behavioral Sciences, Tabriz University of Medical Sciences,Tabriz-Iran
2Liver and gastrointestinal diseases research center, Cystic Fibrosis Registry, Tabriz University of Medical Sciences, Tabriz-Iran

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Keywords : Adolescent, Anxiety,Cystic Fibrosis, Depression , Frequency Psychiatric disorders
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Objectives: Cystic fibrosis is a progressive genetic disorder.According to our knowledge no studies about psychiatric disorders in cystic fibrosis patients were published in Iranuntil now.The goal of this research is to determination frequencyof psychiatric disorders in patients with cystic fibrosis aged 5-18 years in the northwest of Iran who referred to the Cystic Fibrosis clinic of Tabriz Children’s Hospital.

Material and Methods: In this descriptive cross-sectional study, a demographic questionnaire andthe Farsi version of Kiddie Schedule for Affective Disorders and Schizophrenia-present and lifetime (K-SADS-PL,a semi-structured interview) were administered to  determine the psychiatric disorders for 40 patients with cystic fibrosis aged 5-18 years which includes 24 boys and 16 girls attending the Cystic Fibrosis clinic of Tabriz Children's Hospital.

Results: This study consisted of 24 boys (60%) and 16 girls (40%).Separation anxiety disorder was the most common psychiatric disorder in this study(52.5%), followed byoppositional defiant disorder(35%), major depressive disorder(35%), general anxiety disorder(32.5%) and enuresis(22.5%).

The average age of patients was 9.95±0.85 years.The frequency of major depressive disorder in patients over 11 years old was significantly higher. Separation anxiety disorder wasmore represented in girls in both age groups of study, whileenuresis was significantly more represented in boys of two age groups.

Conclusion: The importance of screening psychiatric disorders was cleared according to high frequencyof psychiatricdisorders in patients with cystic fibrosis. Also early determination of psychiatric disorders allows for early referral to psychiatric service and may lead to improve their life quality.


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Javadi, Leila
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