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E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Jan 2019, Vol 6, Issue 1
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Original Article
The Frequency of Psychiatric Disorders in Cystic Fibrosis Patients Aged 5-18 Years in Northwest of Iran
Seyedeh Shaghayegh Hosseinzadeh1, Mandana Rafeey2, Leila Vahedi2, Seyed Gholamreza Noorazar1
1Research Center of Psychiatry and Behavioral Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
2Liver and Gastrointestinal Diseases Research Center, Cystic Fibrosis Registry, Tabriz University of Medical Sciences, Tabriz, Iran

CJMB 2019; 6: 056-060

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Keywords : Cystic fibrosis, Child, Adolescent, Psychiatric disorders, Depression, Frequency, Anxiety
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Abstract
Objectives: Cystic fibrosis (CF) is a progressive genetic disorder. So far, no study, to the best of our knowledge, has investigated the psychiatric disorders of CF patients in Iran. Therefore, the present research aimed to determine the frequency of psychiatric disorders in patients with CF.

Materials and Methods: A number of 40 patients (24 boys vs. 16 girls) with CF within the age range of 5-18 years were included in this descriptive cross-sectional study, who attended the CF Clinic of Tabriz Children"s hospital. A demographic questionnaire and the Farsi version of Kiddie Schedule for Affective Disorders and Schizophrenia-present and lifetime (K-SADS-PL, a semi-structured interview) were administered to determine the psychiatric disorders of these patients.

Results: Based on the results, separation anxiety was the most common psychiatric disorder (52.5%) among the patients followed by oppositional defiant (35%), major depressive (35%), general anxiety (32.5%), and enuresis (22.5%) disorders. The average age of the patients was 9.95 ± 0.85 years. In addition, the frequency of major depressive disorder was significantly higher in patients above 11 years old. Finally, the incidence of separation anxiety disorder was higher in girls within both age groups while enuresis disorder was significantly more frequent in boys of two age groups.

Conclusions: The importance of screening psychiatric disorders was identified based on a high frequency of psychiatric disorders in patients with CF. Therefore, early determination of psychiatric disorders allows for early referral to psychiatric services and thus may result in improving their life quality.

 

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Aras Part Medical International Press Editors in Chief
Arash Khaki
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Zafer Akan Deputy Editor
Javadi, Leila
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