Vitamin D Deficiency May Be a Modifiable Risk Factor in Women With Endometriosis

Marzieh Derakhshan; Maryam Derakhshan; Pegah Hedayat; Maryam Shiasi; Erfan Sadeghi

E-ISSN : 2148-9696

Crescent Journal of
Medical and Biological Sciences

Main Page Aim and Scope Instructions to Authors Editorial Policies Editorial Board Authorship Agreement Form Open Access and Copyright

Oct 2018, Vol 5, Issue 4

CURRENT ISSUE ARCHIVE AHEAD OF PRINT / ACCEPTED ARTICLE MOST VIEWED ARTICLES NEWS RELATED LINKS

Advanced Search

For Author's & Reviewer's

Committee on Publication
Ethics (COPE) Flowchart

Recommendations for the Conduct

World Association of Medical Editors(WAME)

EQUATOR Resources : Reviewers

Poll

How do you find the scientific quality of the published articles on our web site?

Very good

Good

Fair

Bad

Very bad

Original Article
Vitamin D Deficiency May Be a Modifiable Risk Factor in Women With Endometriosis
Marzieh Derakhshan^1,2, Maryam Derakhshan³, Pegah Hedayat³, Maryam Shiasi¹, Erfan Sadeghi⁴
¹Department of Anatomy, Tehran University of Medical Sciences, Tehran, Iran ²Gynecology and Andrology Center, Khanevadeh Hospital, Esfahan, Iran ³Department of Pathology, Isfahan University of Medical Sciences, Isfahan, Iran. ⁴Department of Biostatistics and Epidemiology, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran
CJMB 2018; 5: 292-296 Viewed : 3399 times Downloaded : 2187 times. Keywords : Vitamin D deficiency, Endometriosis, Calcium intake
Full Text(PDF) \| Related Articles
Abstract

Objectives: This study aimed to determine the levels of 25(OH) D in endometriosis patients and to clarify the association between the endometriosis and dietary intake of calcium and vitamin D. Materials and Methods: A total of 200 women with endometriosis as endometriosis group and 154 healthy women (control group) of reproductive age were included in this study. The plasma 25(OH) D (vitamin D3) level was measured by high-pressure liquid chromatography method in endometriosis and control (healthy) groups. Participants in these 2 groups were asked about the dietary intake of calcium and vitamin D. Results: Our result showed the association between 25(OH) D deficiency and endometriosis risk (odds ratio [OR] = 29.4, P < 0.001). The intake of dietary calcium was also inversely associated with recurrence of endometriosis. However, this association was not observed between vitamin D intake and endometriosis. Conclusions: Our results showed that the decreased level of vitamin D (VD) is associated with the endometriosis risk. Accordingly, the authors validate that vitamin D deficiency may be regarded as a predisposing factor for endometriosis. In addition, a decreased risk of endometriosis with increasing calcium (Ca) intake was observed. Therefore, using Ca as dietary supplementation may be useful in the management of endometriosis in patients.