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E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Jul 2018, Vol 5, Issue 3
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Original Article
Impact of Aerobic Exercise on Vaspin in Female Patients With Type 2 Diabetes Mellitus
Zahra Sharaki1, Elham Eftekhari1
1Department of Physical Education and Sport Sciences, Najafabad Branch, Islamic Azad University, Najafabad, Iran

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Keywords : Aerobic exercise, Diabetes Mellitus, Vaspin
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Objective: As a metabolic syndrome,Type 2 diabetes mellitus (T2DM) has had a worldwide increase associated with the incidence of obesity, and Vaspin acts as a new biomarker for obesity and interaction exercise. Our study aimed to survey the effect of aerobic exercise training on Vaspin in female patients with T2DM.

Material and Methods: Forty T2DM female patients(age =33.00 ± 8.08 yrs.) as diagnosed based on the International Diabetes Federation (IDF) were selected. The participants were randomly divided into an exercise (E) and a control group (C). At the beginning and the end of the study, all the variables were measured. Group E participated in eight-week training session's 3d/w for 60 minutes and an intensity of 60-70% of maximum heart rate. The control group continued its usual life.

Results: Thirty-one subjects completed the study period [(E (n=18) and C (n=13)]:Statistical analysis showed that group E had a significant increase in Vaspin (F= 8.888, P= 0.001) and a significant decrease in BM (Body Mass Weight), BMI (Body Mass Index), WC (Waist Circumference), FP (Fat Percentage), FM (Fat Mass), FFM (Fat Free Mass), TC (Total Cholesterol), FBS (Fast Blood Sugar) and Insulin, whereas there was no significant change in HC (Hip Circumference ), WHR (Waist to Hip ratio), TG (Triglyceride), HOMA-IR, and QUICKI in the exercise group compared with the control group (P < 0.05).

Conclusion: Our data suggest that Vaspin behavior is reversed by increasing duration and progressive stage of (T2DM) and increases following exercise and loss weight.


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Javadi, Leila
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