|Association of Pulmonary Function Tests and Serum Vitamin D Levels in Asthmatics With Vitamin D Deficiency|
|Mahnaz Amini1, Zahra Mirfeizi2, Houshang Rafatpanah3, Leila Ghofraniha1, Shahrzad Mohammadzadeh Lari1, Saeid Eslami4,5, Habibollah Esmaily6, Mostafa Abasalti1|
|1Lung Disease Research Center, Faculty of Medicine, Mashhad University of Medicine Sciences, Mashhad, Iran
2Rheumatic Diseases Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
3Inflammation and Inflammatory Diseases Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
4Pharmaceutical Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
5Department of Medical Informatics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
6Department of Biostatistics, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran
CJMB 2018; 5: 021-024
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Keywords : Asthma, Vitamin D, Respiratory function test
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Objective: The effects of serum vitamin D levels on the evolution or severity of asthma have been widely researched; however, conflicting results have been achieved. This study was designed to evaluate the relationship between serum vitamin D levels and pulmonary function tests in asthmatic and non-asthmatic people with vitamin D deficiency.
Materials and Methods: This was a prospective cross-sectional study on healthy adults and asthmatic patients. Standard spirometry and serum 25-hydroxyvitamin D test were performed for all participants.
Results: Forty asthmatic patients and 40 healthy controls were tested. The mean age of participants was 42.86 ± 1.6. High prevalence of vitamin D deficiency was found in both the asthmatic and control groups. No significant correlation was found between serum vitamin D levels and spirometry parameters in either of the groups (P = 0.83).
Conclusion: Serum levels of 25-hydroxyvitamin D were not correlated with the severity of asthma as evaluated by pulmonary function tests in asthmatics.
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