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E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Jan 2018, Vol 5, Issue 1
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Association of Pulmonary Function Tests and Serum Vitamin D Levels in Asthmatics of a Vitamin D Deficient Population
Mahnaz Amini1, Zahra Mirfeizi2, Houshang Rafatpanah3, Leila Ghofraniha1, Shahrzad Mohammadzadeh Lari1, Saeid Eslami4,5, Habibollah Esmaily6, Mostafa Abasalti1
1Lung Disease Research Center, Faculty of Medicine Mashhad University of Medicine Sciences, Mashhad, Iran
2Rheumatic Diseases Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
3Inflammation and Inflammatory Diseases Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
4Pharmaceutical Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
5Department of Medical Informatics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
6Department of Biostatistics, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran


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Keywords : Asthma, Vitamin D, Respiratory Function Test
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Abstract
Background: The effects of serum vitamin D levels on its evolution or its severity have been widely researched, however, with conflicting results. This study was designed to evaluate the relation between serum Vitamin D levels and pulmonary function tests in asthmatics of Vitamin D deficient population.

Methods: This was a prospective cross-sectional study on healthy adults and asthmatic patients. Standard spirometry and measurements of serum 25 hydroxy Vitamin D were performed for all participants.

Results: Forty asthmatic patients and 40 healthy controls were tested. The mean age of participants was 42.86 ± 1.6. High prevalence of Vitamin D deficiency was found in both the asthmatic/control groups. No significant correlation was found between serum Vitamin D levels and spirometry parameters in either of the groups (p=0.83).

Conclusions: Serum levels of 25 hydroxy Vitamin D were not correlated with the severity of asthma as evaluated by pulmonary function tests in asthmatics.

 

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Articles by Amini M
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Articles by Mahnaz Amini
Articles by Zahra Mirfeizi
Articles by Leila Ghofraniha
Articles by Saeid Eslami
Articles by Habibollah Esmaily
Articles by Mostafa Abasalti

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Arash Khaki
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Zafer Akan Deputy Editor
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