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E-ISSN : 2148-9696
Crescent Journal of
Medical and Biological Sciences
Jan 2018, Vol 5, Issue 1
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Original Article
Comparison of Epidural Methylprednisolone, Bupivacaine, Normal Saline Injection in Chronic Backache due to Discal Hernia
Naghi Abedini1, Hojjat Pourfathi2, Maghsoud Eskandari3, Masoud Parish4
1Department of Anesthesiology, Tabriz University of Medical Sciences,Tabriz, Iran
2Department of Anesthesiology, Taleghani Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
3Department of Anesthesiology, Taleghani Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
4Department of Anesthesiology, Tabriz University of Medical Sciences,Tabriz, Iran


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Keywords : Backache, Epidural Methyylprednisolone, Bupivacaine, Normal Saline injection
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Abstract
Objectives: Low back pain is the most common skeletal- muscular complaints requiring medical care and causes many complications and social and economical damages in society and is the fifth most common reason for physician visit especially among men. The purpose of this study was Comparison of Epidural Methylprednisolone, Bupivacaine and Normal Saline injection in chronic low back pain due to discal hernia.

Material and methods: This study was a randomized , single-blind , clinical trial which was conducted on patients with chronic low back pain, and the impact of Epidural Methylprednisolone, Bupivacaine and Normal Saline injection was studied. In first group, 80 mg of Methylprednisolone prepared in 10 cc volume, in second group, it was local anesthesia drug, Bupivacaine 0.5% (10 ml) and in third group, it was 10 ml of Normal Saline solution (equal injected volumes). During injection, the patient was being monitored in terms of pain, hemodynamic, consciousness, arterial oxygen saturation. Results: The severity of pain in Methylprednisolone group three months after treatment was less and rate of disability, in Normal Saline group after three months was significantly more (p<0/001) and also disability reduction rate in Methylprednisolone group significantly was more (p<0/001). In our study, average time to return to daily activities in Normal Saline patients was significantly more (p=0/005).

Conclusion: Epidural Methylprednisolone, Bupivacaine injection was more effective than Placebo (normal saline) injection in these patients.

 

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Aras Part Medical International Press Editors in Chief
Arash Khaki
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Zafer Akan Deputy Editor
Javadi, Leila
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